Autism Spectrum Disorder (ASD) is a neuropsychological condition that affects behavior and communication. Irritability is a common symptom, manifesting as outbursts of anger and difficulties with changes. Transcranial Direct Current Stimulation (tDCS) is a promising technique for modulating these symptoms.

Investigating the effect of tDCS combined with virtual reality on reducing irritability in children with ASD.

A quasi-experimental study was conducted with 18 children diagnosed with ASD. The Childhood Autism Rating Scale (CARS) and the Affective Reactivity Index (IRA) were administered before and after the intervention. For statistical analysis, the Shapiro-Wilk test and paired t-test were used.

There was a statistically significant difference in irritability levels after the intervention (p = 0.00), suggesting that tDCS had a positive impact on reducing the symptom.

tDCS combined with virtual reality demonstrated efficacy in reducing irritability in children with ASD, making it a promising alternative for managing these symptoms.

The results reinforce the need for randomized clinical trials to confirm the effects of tDCS and its clinical applicability.