Chikungunya has a high incidence in various areas of Brazil, representing a significant public health challenge. The disease overwhelms healthcare services and affects the ability to work and maintain professional activities among infected individuals.

To analyze the epidemiological profile and the prevalence of painful symptoms among suspected and confirmed cases of Chikungunya fever in a state of the Northern region of Brazil, from 2016 to 2021.

This is an observational, retrospective, and ecological study. Data on reported cases were collected from notification forms in the Notifiable Diseases Information System (SINAN). The sample included confirmed and suspected cases of Chikungunya fever, involving individuals of both sexes and all age groups from a state in the Northern region of Brazil, between 2016 and 2021. Variables such as sex, age, race, education level, and symptoms were analyzed. Data analysis was performed using Jamovi software (2.3.28), with results presented in frequencies, mean, standard deviation, and percentages.

A total of 854 individuals were included, comprising 482 suspected and 372 confirmed cases, with a predominance of females (55.7%), a mean age of 31.8 years (±18.5), and the highest prevalence in the 30–59 age group (45.7%). The ethnic distribution showed a predominance of mixed-race individuals (pardos), accounting for 77.4% (n = 661), while 15% (n = 128) of participants had an education level up to high school. Among pain-related symptoms, myalgia was observed in 73.3% (n = 640) of cases (297 confirmed and 343 suspected), and back pain in 57.1% (n = 485) (221 confirmed and 264 suspected).

The predominance of cases among working-age women with low educational attainment suggests greater exposure to the vector and potential gaps in vector control. Furthermore, the high prevalence of painful symptoms may compromise the quality of life and functionality of affected individuals.

The study highlights the need for effective strategies for vector prevention and clinical management of Chikungunya, considering the observed clinical and demographic characteristics, to minimize the impact of the disease on the daily lives of affected individuals.