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Vol. 28. Issue S1.
1st STUDENT SCIENTIFIC CONFERENCE OF THE BRAZILIAN ASSOCIATION FOR RESEARCH AND POSTGRADUATE IN PHYSIOTHERAPY (ABRAPG-FT)
(01 April 2024)
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Vol. 28. Issue S1.
1st STUDENT SCIENTIFIC CONFERENCE OF THE BRAZILIAN ASSOCIATION FOR RESEARCH AND POSTGRADUATE IN PHYSIOTHERAPY (ABRAPG-FT)
(01 April 2024)
401
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PRELIMINARY DATA ON THE EFFECTS OF PHOTOBIOMODULATION ON TISSUE REPAIR OF BURNING INJURIES: A RANDOMIZED, CONTROLLED, DOUBLE-BLINDED CLINICAL TRIAL
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Silvana Cristina de Araújo Pereira Venceslau1, Renata Maria Freire Barros1, Ronny Marcos de Morais1, Maria Lavínia de Oliveira Alves1, Palloma Rodrigues de Andrade1, Heleodório Honorato dos Santos1
1 Postgraduate Program in Physical Therapy, Federal University of Paraíba (PPG-Fis / UFPB), João Pessoa, Paraíba, Brazil
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Vol. 28. Issue S1

1st STUDENT SCIENTIFIC CONFERENCE OF THE BRAZILIAN ASSOCIATION FOR RESEARCH AND POSTGRADUATE IN PHYSIOTHERAPY (ABRAPG-FT)

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Background

Burning is a tissue injury that can be treated through photobiomodulation, which promotes tissue repair by activating physiological cascades that induce the synthesis of RNA and DNA, increasing the production of new cells. LEDtherapy is a type of phototherapeutic resource that uses photobiomodulation, this resource provides a cheaper treatment, easy to apply with less time when compared to LASERtherapy, this is due to the characteristics of LED light. However, there is a scientific gap, as the studies that have been developed in recent years report the effects of LASER in animal models or in vitro, little is known about the real effect of the treatment of burns with LED in human beings, thinking about it, the idea arose. hypothesis of what is the effect of this resource in human model.

Objectives

To compare the effect of red LED photobiomodulation, infrared LED and sham therapy on the rate of re-epithelialization, presence of pain, pruritus, skin temperature, healing quality and scar mobility among individuals with second-degree burns.

Methods

This is a double-blind randomized controlled clinical trial. 11 burn injuries were treated, divided into 3 groups: Red Led Group (n = 2), Infrared LED Group (n = 5), and Sham Group (n = 4), the group's stimulation by LED an application of 7J/cm² per point, in the Shan group, the application was mimicked. The presence of pain, itching, skin temperature and wound size were evaluated daily until healing, and at the end of healing, the mobility and quality of the scar were evaluated. Data were analyzed using descriptive statistics, re-epithelialization rate, skin temperature and scar mobility, ANOVA was performed for repeated measures, by Bonferroni post-hoc. One-way anova and for Kruskall wallis scar quality considering a significance level of P ≤ 0.05.

Results

There was no statistical difference for the outcome pain, pruritus, rate of re-epithelialization and scar mobility and quality between the groups. However, it is possible to observe a clinical improvement in rate of re-epithelialization, pain and itching in the stimulation groups when compared to the shan.

Conclusion

It is necessary to be careful about the inferences made regarding the results of this research due to the low statistical power, however, it is possible to observe a clinical improvement in the volunteers who were treated with led therapy, the re-epithelialization rate and pain resolution and pruritus in the initial 48 hours.

Implications

The development of studies like this one can answer doubts about the use of LED therapy in wounds in general, and in addition can generate new perspectives for the treatment of burned patients, and insert the physiotherapist even more in the rehabilitation of these patients, thinking of a more uniform and organized healing, with fewer physical sequelae.

Keywords:
Photobiostimulation
Healing
Reepithelialization
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Conflict of interest: The authors declare no conflict of interest.

Acknowledgment: I thank the research team the volunteers who made themselves available to be part of this study.

Ethics committee approval: Approved by the Research Ethics Committee of the Health Sciences Center (CEP/CCS) under protocol nº 4.003.229, CAAE: 30671820.1.0000.5188 and registered in the Brazilian Registry of Clinical Trials - RBR-8bfznx6.

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Brazilian Journal of Physical Therapy
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