The acute phase of Covid-19 in patients with a higher burden of disease and aggravating risk factors is characterized by the occurrence of a multisystemic inflammatory syndrome. Regarding the complications described the development of acute kidney injury has been associated with the occurrence of worse outcomes, higher morbimortality and complications in human functionality.

To assess the presence of lifestyle habits and the occurrence of changes in kidney function at admission and after the acute phase of Covid-19 in subjects that were hospitalized.

Cross-sectional study, conducted from March to September 2021 in post-intensive care nucleus of the university hospital. That were included men and women aged 35-75 years with laboratory confirmation of Covid-19 and creatinine result. Lifestyle habits such as smoking, and alcoholism and comorbidities (at the hospital admission and discharge) were considered and evaluated. Data about the period of admission to the intensive care unit (ICU) and hospital in days were also included. The kidney function was evaluated according to serum creatinine levels (Crs) and estimate glomerular filtration rate (eGFR), that it is an estimate of the rate of clearance of Crs by the kidneys, it was calculated by the CKD/EPI equation in the patient's admission and after hospital discharge. The results were presented with relative and absolute frequencies and mean and standard deviation.

37 patients with an average age of 56.61 ±10.04 years were evaluated, 51.4% (n=19) were women and 29.7% (n=11) were smokers and alcoholics. The most common comorbidities in the hospital admission were a high blood pressure 70,2% (n=26), obesity 56.7% (n=21), dyslipidemias 29.7% (n=11), diabetes mellitus type 2 29.7% (n=11), coronary artery disease 10.8 % (n=4). After the Covid-19, this number increased of 2.7%, 13.7%, 5.4, 5.4% and 2.7%, respectively. The average period of days in the ICU and hospital was 16.94 ±14.29 and 31.48 ±20.97 respectively. Concerning the Crs level, 27% (n=10) of the sample presented elevation, which led to the need for hemodialysis.

Individuals with a history of smoking, alcohol consumption and multiple comorbidities evolved with kidney function change after the acute phase of Covid-19.

The kidney functionality of individuals with higher burden of disease may be compromised in the short and medium term after the acute phase of Covid-19.